Endonyx toenail onychomycosis caused by Trichophyton rubrum: treatment with photodynamic therapy based on methylene blue dye*
نویسندگان
چکیده
This study shows the effectiveness of photodynamic therapy based on methylene blue dye for the treatment of endonyx toenail onychomycosis. Four patients with endonyx onychomycosis caused by Trichophyton rubrum were treated with 2% methylene blue aqueous solution irradiated with light emission diode at 630 nm and an energy density of 36 J/cm2 for 6 months at 2-week intervals. The preliminary study showed the effectiveness of this therapy in the treatment of endonyx onychomycosis, and also indicated that the disease can be caused by T. rubrum.
منابع مشابه
Distal and lateral toenail onychomycosis caused by Trichophyton rubrum: treatment with photodynamic therapy based on methylene blue dye*
The study showed the effectiveness of photodynamic therapy based on methylene blue to treat severe distal and lateral subungual toenail onychomycosis. 22 patients were divided into two groups: group A consisting of 11 patients with severe toenail onychomycosis and group B consisting of 11 patients with mild-to-moderate toenail onychomycosis. All patients had onychomycosis caused by Trichophyton...
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1. Ruíz-Cendoya M, Madrid H, Pastor FJ, Mayayo E, Mariné M, Guarro J. Development of murine models of disseminated infection by Neoscytalidium dimidiatum. Med Mycol. 2010;48: 681--6. 2. Downs AM, Lear JT, Archer CB. Scytalidium hyalinum onychomycosis successfully treated with 5% amorolfine nail lacquer. Br J Dermatol. 1999;140:555. 3. Dunand J, Viguie C, Paugam A. Intermittent posaconazole regi...
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During 12 months survey on 33 patients with onychomycosis, only one of them showed infection due to scopulariopsis brevicalis. The case was a 38-year-old male with great toe nail lesion which was diagnosed as Trichophyton rubrum based on smear and culture. The patient was treated with 3 weekly pulses of itraconazole, 200mg twice daily during 3 months and showed marked clinical improvement. But ...
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Since the early 20th century, onychomycosis originated with the onset of war, the use of occlusive footwear, and the mass migration of people by transportation in the United States. Even though onychomycosis has a high prevalence in the US, other parts of the world including Canada, West Africa, Southeast Asia, Northern Australia, and Europe have been well documented with cases of fungal toenai...
متن کاملThe association of fractional CO2 laser 10.600nm and photodynamic therapy in the treatment of onychomycosis*
BACKGROUND Onychomycosis is a fungal infection of the nails caused in most cases by dermatophytes Trichophyton rubrum and Trichophyton mentagrophytes. Despite numerous available antifungal drugs for therapy of this infection, the cure rate is low, with high rates of relapse after treatment and side effects. OBJECTIVES To present a new option for the treatment of onychomycosis, in search of a ...
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